Nameless simplicity is the 'cure' for desire, which arises from giving names to things, thus creating the Ten thousand Things.
Basically, everything is how it is, part of the All, and always changing.
We humans (and all other living creatures) perceive reality in a certain way. From here, a need arises to define that what we perceive. In taoism, this is called the birth of the Ten Thousand Things. In a way, our defining them gives birth to objects, words and everything else that exists for us. Of course, matter and energy will still exist if we do not define it.
We need these definitions to live our lives. We need to define objects, to be able to order them. We need to define words, to be able to communicate.
This is our way. However, from defining stuff, we attribute a value to it. And this is where the problems begin.
The desire to speak, the desire to act.
Returning to the Nameless simplicity (as given in verse #37) is a way of stripping something (whether it is an object, an act, a word, or a life) of its attributed value. Returning it to its source, just being a non-defined part of the All, and it will have no value.
So, whenever you feel your desires acting up, you can try to picture the object of your desire as humanly defined entity, and from there return it to the great All. You may cherish it, you may love it, but you should not let your actions or words be guided by the value that it holds in your mind. Love it for what it is, not for what you want it to be.